TB-500, the synthetic analog of the endogenous peptide Thymosin Beta-4, represents a breakthrough in regenerative medicine research due to its multifaceted biological activities:

• Comprehensive Tissue Repair Mechanisms: TB-500 demonstrates remarkable upregulation of cell migration through actin polymerization, facilitating accelerated wound closure and tissue remodeling in experimental models.
• Anti-Inflammatory Properties: Research indicates significant downregulation of pro-inflammatory cytokines (IL-1β, TNF-α) while promoting anti-inflammatory factors, making it valuable for studying chronic inflammatory conditions.
• Angiogenesis Modulation: The peptide enhances vascular endothelial growth factor (VEGF) expression, supporting research into ischemic injury recovery and microcirculation improvement.
• Neuroprotective Potential: Preliminary studies suggest neuroregenerative effects through modulation of neuronal differentiation factors, relevant for CNS injury research.

Advanced Nasal Delivery System

This 10mg formulation (50 precisely calibrated sprays) offers researchers:

• Superior bioavailability compared to traditional administration routes
• Blood-brain barrier penetration for neurological studies
• Real-time pharmacokinetic monitoring capabilities
• Non-invasive repeat dosing for longitudinal study designs

Storage and Handling Protocol

• Optimal Storage: Maintain at 20-25°C in amber vials; desiccant-protected environments recommended for long-term stability.
• Sterile Procedures: Requires biosafety cabinet (Class II) handling with ethanol sterilization of administration components.

Research Administration Guidelines

• Dosing Precision: Each actuation delivers 200μg (±5% variance) of pharmaceutical-grade TB-500, validated by HPLC analysis.
• Protocol Design: Ideal for studies requiring q12h-q24h dosing intervals with minimal subject stress.