Description
Semaglutide is a synthetic GLP-1 analog that has revolutionized metabolic research through its dual actions on glucose regulation and appetite suppression. As a long-acting peptide with 94% albumin binding capacity, it enables researchers to study sustained metabolic effects in experimental models. The nasal spray formulation (10mg/vial, 50 metered sprays) provides a non-invasive delivery method ideal for chronic study protocols.
Key research applications include:
- Pancreatic function studies – glucose-dependent insulin secretion and β-cell proliferation
- Central metabolic regulation – hypothalamic appetite control via nasal-blood-brain barrier passage
- Adipose tissue research – lipid metabolism and fat storage modulation
Storage and Handling Protocol
- Storage Conditions: Stable at 15-30°C in original packaging
- Handling Requirements: Aseptic technique with ethanol-sanitized components
Research Administration
- Precision Delivery: Consistent 0.2mg (±5%) per spray, validated by mass spectrometry
- Study Design: Optimized for q48h dosing in 12-week metabolic protocols
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